Multifunctional plasmonic nanorattles for spectrum-guided locoregional therapy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24151211.
- Also identified by DOI 10.1002/adma.201302803.
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Abstract
Locoregional death of cancer cells (in vitro) is induced by ablation of plasmonic nanorattles combined with triggered release of a chemotherapeutic drug from the nanorattles. Completion of the therapy process is indicated by a "Raman signal flip" between the two reporters of the surface-enhanced Raman scattering (SERS) probe. The nanorattles enable targeted delivery of payload and simultaneous monitoring of the payload release and the therapy process.
Medical subject headings
- Antineoplastic Agents
- Drug Delivery Systems
- Metal Nanoparticles
- Nanocapsules