Structural biology: Pivotal findings for a transcription machine.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24153180.
- Also identified by DOI 10.1038/nature12700 and PMC identifier 4416112.
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Abstract
Crystal structures of the complete RNA Polymerase I complex are now revealed. These structures link opening and closing of the DNA binding cleft of this enzyme to control of transcription.
Medical subject headings
- Gene Expression Regulation
- Protein Subunits
- RNA Polymerase I
- Saccharomyces cerevisiae
- Transcription, Genetic