The context of blood vessels and response to VEGF-targeted therapy.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24166904.
- Also identified by DOI 10.1158/1078-0432.CCR-13-2479.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Although therapy directed against VEGF has produced clinical benefit, an understanding of responsive tumor characteristics is lacking. Blood vessel location relative to tumor cells and stromal factors may influence tumor susceptibility to VEGF-targeted therapy. Clinical validation of this potential biomarker is needed to influence clinical practice.
Medical subject headings
- Antibodies, Monoclonal, Humanized
- Neoplasms
- Stromal Cells
- Vascular Endothelial Growth Factor A