A transcriptional signature for active TB: have we found the needle in the haystack?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24167454.
- Also identified by DOI 10.1371/journal.pmed.1001539 and PMC identifier 3805486.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Adithya Cattamanchi and colleagues reflect on recent research by Michael Levin and coworkers into the use of whole blood mRNA expression signatures to detect tuberculosis. The authors highlight challenges faced in getting this promising technology into clinics in low-resource settings. Please see later in the article for the Editors' Summary.
Medical subject headings
- HIV Infections
- RNA
- Tuberculosis