Concordance of resistance profiles in households of patients with multidrug-resistant tuberculosis.

Parr, Jonathan B; Mitnick, Carole D; Atwood, Sidney S; Chalco, Katiuska; Bayona, Jaime; Becerra, Mercedes C · Clin Infect Dis · 2014

retrospective_cohort · Level III

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Abstract

We estimated the proportion of household contacts whose drug-susceptibility test results matched those of the purported source patient with multidrug-resistant tuberculosis. Ninety-nine (88.4%) contacts had isolates resistant to isoniazid and rifampin, and 41 (36.6%) contacts had isolates with results that also matched the purported source for ethambutol, streptomycin, and pyrazinamide.

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