MetaboNetworks, an interactive Matlab-based toolbox for creating, customizing and exploring sub-networks from KEGG.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24177720.
- Also identified by DOI 10.1093/bioinformatics/btt612 and PMC identifier 3957072.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
MetaboNetworks is a tool to create custom sub-networks in Matlab using main reaction pairs as defined by the Kyoto Encyclopaedia of Genes and Genomes and can be used to explore transgenomic interactions, for example mammalian and bacterial associations. It calculates the shortest path between a set of metabolites (e.g. biomarkers from a metabonomic study) and plots the connectivity between metabolites as links in a network graph. The resulting graph can be edited and explored interactively. Furthermore, nodes and edges in the graph are linked to the Kyoto Encyclopaedia of Genes and Genomes compound and reaction pair web pages. MetaboNetworks is available from http://www.mathworks.com/matlabcentral/fileexchange/42684. jmp111@ic.ac.uk or j.nicholson@imperial.ac.uk Supplementary data are available at Bioinformatics online.
Medical subject headings
- Metabolomics