m(6)A mRNA methylation: a new circadian pacesetter.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24209613.
- Also identified by DOI 10.1016/j.cell.2013.10.028.
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Abstract
The purpose of m(6)A methylation of RNA, first observed in the 1970s, has been a longstanding mystery. Fustin et al. now show that it regulates RNA processing and determines the period and oscillatory stability of the mammalian circadian clockwork.
Medical subject headings
- Circadian Clocks
- Methyltransferases
- RNA
- RNA Processing, Post-Transcriptional