The frustrated gene: origins of eukaryotic gene expression.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24209615.
- Also identified by DOI 10.1016/j.cell.2013.10.003 and PMC identifier 4163148.
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Abstract
Eukarytotic gene expression is frustrated by a series of steps that are generally not observed in prokaryotes and are therefore not essential for the basic chemistry of transcription and translation. Their evolution may have been driven by the need to defend against parasitic nucleic acids.
Medical subject headings
- Biological Evolution
- DNA Transposable Elements
- Eukaryotic Cells
- Gene Expression
- Viruses