Cytokines make an indelible impression on neural stem cells.

Cope, Elise C; Gould, Elizabeth · Cell Stem Cell · 2013

editorial · Level V

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Abstract

Infections during pregnancy have been associated with increased risks of neuropsychiatric disorders in offspring, although the underlying mechanisms have not been determined. Gallagher et al. (2013) show that maternal exposure to the infection-induced inflammatory cytokine IL-6 produces lasting effects on forebrain stem cell pools of offspring during embryogenesis and throughout life.

Medical subject headings