A new image of the hematopoietic stem cell vascular niche.

Silberstein, Leslie E; Lin, Charles P · Cell Stem Cell · 2013

editorial · Level V

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Abstract

The microenvironment within the bone marrow that maintains hematopoietic stem cell (HSC) quiescence is the subject of intense study. In a recent Nature paper, Kunisaki et al. combine imaging techniques and computational modeling to define a novel arteriolar niche for quiescent HSCs within the bone marrow.

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