PSAR-align: improving multiple sequence alignment using probabilistic sampling.
Where this comes from
- Record sourced from PubMed, PMID 24222208.
- Also identified by DOI 10.1093/bioinformatics/btt636 and PMC identifier 3967100.
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Abstract
We developed PSAR-Align, a multiple sequence realignment tool that can refine a given multiple sequence alignment based on suboptimal alignments generated by probabilistic sampling. Our evaluation demonstrated that PSAR-Align is able to improve the results from various multiple sequence alignment tools. The PSAR-Align source code (implemented mainly in C++) is freely available for download at http://bioen-compbio.bioen.illinois.edu/PSAR-Align.
Medical subject headings
- High-Throughput Nucleotide Sequencing
- Software