Deciphering laminar-specific neural inputs with line-scanning fMRI.
basic_science · Level V
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- Record sourced from PubMed, PMID 24240320.
- Also identified by DOI 10.1038/nmeth.2730 and PMC identifier 4276040.
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Abstract
Using a line-scanning method during functional magnetic resonance imaging (fMRI), we obtained high temporal (50-ms) and spatial (50-μm) resolution information along the cortical thickness and showed that the laminar position of fMRI onset coincides with distinct neural inputs in rat somatosensory and motor cortices. This laminar-specific fMRI onset allowed us to identify the neural inputs underlying ipsilateral fMRI activation in the barrel cortex due to peripheral denervation-induced plasticity.
Medical subject headings
- Magnetic Resonance Imaging
- Motor Cortex
- Neuronal Plasticity
- Neurons