First steps toward a globally effective HIV/AIDS vaccine.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24243006.
- Also identified by DOI 10.1016/j.cell.2013.10.012.
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Abstract
The enormous diversity of HIV-1 presents a formidable challenge for developing an effective AIDS vaccine. In this issue of Cell, Barouch et al. show that bioinformatically designed antigens, pieced together from multiple HIV immune epitopes, partially protect rhesus macaques from simian-human immunodeficiency virus infection. This "mosaic" approach holds promise for the development of broadly protective vaccines.
Medical subject headings
- AIDS Vaccines
- HIV-1