Exploring concentration response in HIV pre-exposure prophylaxis to optimize clinical care and trial design.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24243011.
- Also identified by DOI 10.1016/j.cell.2013.09.030.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
HIV pre-exposure prophylaxis trials with antiretroviral drugs have been variably successful. Even trials demonstrating the best efficacy leave room for improvement. Pharmacological data illuminate several sources of outcome variability, especially the impact of poor adherence, which is critical to manage PrEP in the clinic and to develop the next generation of PrEP candidates.
Medical subject headings
- Anti-HIV Agents
- HIV Infections