Ultrasound-triggered regulation of blood glucose levels using injectable nano-network.

Di, Jin; Price, Jennifer; Gu, Xiao; Jiang, Xiaoning; Jing, Yun; Gu, Zhen · Adv Healthc Mater · 2014

basic_science · Level V

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Abstract

The integration of an injectable insulin-encapsulated nano-network with a focused ultrasound system (FUS) can remotely regulate insulin release both in vitro and in vivo. A single subcutaneous injection of the nano-network with intermittent FUS administration facilitates reduction of the blood glucose levels in type 1 diabetic mice for up to 10 d.

Medical subject headings