A retrospective assessment of the incidence of respiratory depression after neuraxial morphine administration for postcesarean delivery analgesia.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 24257387.
- Also identified by DOI 10.1213/ANE.0b013e3182a9b042.
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Abstract
Respiratory depression can occur after neuraxial morphine administration. In the obstetric population, there are little data on respiratory depression after neuraxial morphine administration in women undergoing cesarean delivery. In this single-center, retrospective study in 5036 obstetric patients (mean body mass index = 34 kg/m) who underwent cesarean delivery and received neuraxial morphine, we did not identify any instances of respiratory depression requiring naloxone administration or rapid response team involvement. Therefore, the upper 95% confidence limit for respiratory depression in our study is 0.07% (1 event per 1429 cases).
Medical subject headings
- Analgesics, Opioid
- Cesarean Section
- Morphine
- Postoperative Pain
- Respiratory Insufficiency