Divergent transcription: a driving force for new gene origination?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24267885.
- Also identified by DOI 10.1016/j.cell.2013.10.048 and PMC identifier 3899942.
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Abstract
The mammalian genome is extensively transcribed, a large fraction of which is divergent transcription from promoters and enhancers that is tightly coupled with active gene transcription. Here, we propose that divergent transcription may shape the evolution of the genome by new gene origination.
Medical subject headings
- RNA, Untranslated
- Regulatory Sequences, Nucleic Acid
- Transcription, Genetic