A quantitative liposome microarray to systematically characterize protein-lipid interactions.
basic_science · Level V
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- Record sourced from PubMed, PMID 24270602.
- Also identified by DOI 10.1038/nmeth.2734.
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Abstract
Lipids have a role in virtually all biological processes, acting as structural elements, scaffolds and signaling molecules, but they are still largely under-represented in known biological networks. Here we describe a liposome microarray-based assay (LiMA), a method that measures protein recruitment to membranes in a quantitative, automated, multiplexed and high-throughput manner.
Medical subject headings
- Lipids
- Liposomes
- Microarray Analysis