Micropatterned polymeric nanosheets for local delivery of an engineered epithelial monolayer.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24307219.
- Also identified by DOI 10.1002/adma.201304183.
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Abstract
Like a carpet for cells, micropatterned polymeric nanosheets are developed toward local cell delivery. The nanosheets direct morphogenesis of retinal pigment epithelial (RPE) cells and allow for the injection of an engineered RPE monolayer through syringe needles without the loss of cell viability. Such an ultrathin carrier has the promise of a minimally invasive delivery of cells into narrow tissue spaces.
Medical subject headings
- Nanostructures
- Retinal Pigment Epithelium
- Tissue Engineering
- Tissue Scaffolds