Glucocorticoid rhythm renders female mice more daring.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24315091.
- Also identified by DOI 10.1016/j.cell.2013.11.017.
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Abstract
Glucocorticoids, which have been implied in mood modulation, display robust diurnal oscillations in the blood. But does their circadian rhythm regulate mood swings? Ikeda et al. now identify a paracrine signaling pathway in the adrenal cortex that potentiates the daily amplitude of plasma glucocorticoids and renders female mice braver.
Medical subject headings
- Anxiety
- Circadian Rhythm
- Glucocorticoids
- Receptors, CXCR