The young and the Wnt-less: transplantable fetal intestinal spheroids without Wnts.
basic_science · Level V
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- Record sourced from PubMed, PMID 24315434.
- Also identified by DOI 10.1016/j.stem.2013.11.019 and PMC identifier 3896122.
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Abstract
The differences between fetal and adult intestinal stem cells are unclear, and understanding this relationship could present novel therapeutic opportunities. Fordham et al. (2013) and Mustata et al. (2013) report a potential source of transplantable epithelial cells from fetal gut that can convert into adult intestinal stem and differentiated cells.