The "skinny" on Wnt signaling in stem cells.
review · Level V
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- Record sourced from PubMed, PMID 24315435.
- Also identified by DOI 10.1016/j.stem.2013.11.012.
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Abstract
Although previous reports suggested that canonical Wnt signaling has opposing effects on epidermal and hair follicle stem cells, two recent papers (Choi et al., 2013; Lim et al., 2013) now show that Wnt signaling promotes proliferation in both stem cell populations, revealing new insights into regeneration of both skin compartments.