Mechanisms of obesity-induced gastrointestinal neoplasia.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24315827.
- Also identified by DOI 10.1053/j.gastro.2013.11.051 and PMC identifier 3978703.
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Abstract
Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. In this report, we review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.
Medical subject headings
- Adenocarcinoma
- Gastrointestinal Neoplasms
- Obesity
- Pancreatic Neoplasms