Bedside to bench: The risk of bleeding with parenteral omega-3 lipid emulsion therapy.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 24321533.
- Also identified by DOI 10.1016/j.jpeds.2013.10.066.
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Abstract
Our clinical experience led us to reassess the effect of sole omega-3 lipid therapy on hemostasis. We compared thromboelastography platelet mapping in neonatal piglets given sole omega-3 lipid. We identified abnormalities in reaction time (P = .025) and the arachidonic acid pathway (P = .025). The potential for bleeding complications from parenteral omega-3 lipid emulsion therapy in high-risk infants with liver disease has been dismissed but, on the basis of this data, should be reconsidered.
Medical subject headings
- Fat Emulsions, Intravenous
- Fish Oils
- Hemorrhage
- Parenteral Nutrition