Sono-assembly of highly biocompatible polysaccharide capsules for hydrophobic drug delivery.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24323846.
- Also identified by DOI 10.1002/adhm.201300596.
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Abstract
Cells like sugar. General synthesis and potential of intracellular hydrophobic drug delivery of single-component polysaccharide capsules are pursued. The capsules can be generally assembled through hydrogen bonding networks but show striking shell robustness. The evidenced cell internalization, stimuli-responsiveness to local pH changes and high biocompatibilities of the capsules specifically favor their potential intracellular drug delivery.
Medical subject headings
- Biocompatible Materials
- Capsules
- Drug Carriers
- Pharmaceutical Preparations
- Polysaccharides
- Sonication