Replicability and heterogeneity of awake unrestrained canine FMRI responses.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24324719.
- Also identified by DOI 10.1371/journal.pone.0081698 and PMC identifier 3852264.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Previously, we demonstrated the possibility of fMRI in two awake and unrestrained dogs. Here, we determined the replicability and heterogeneity of these results in an additional 11 dogs for a total of 13 subjects. Based on an anatomically placed region-of-interest, we compared the caudate response to a hand signal indicating the imminent availability of a food reward to a hand signal indicating no reward. 8 of 13 dogs had a positive differential caudate response to the signal indicating reward. The mean differential caudate response was 0.09%, which was similar to a comparable human study. These results show that canine fMRI is reliable and can be done with minimal stress to the dogs.
Medical subject headings
- Magnetic Resonance Imaging
- Wakefulness