Fly model causes neurological rethink.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 24336781.
- Also identified by DOI 10.7554/eLife.01820 and PMC identifier 3859177.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A Drosophila model for a neurological disorder called type 2B Charcot-Marie-Tooth disease reveals that it has its origins in a partial loss of function, rather than a gain of function, which points to the need for a new therapeutic approach.
Medical subject headings
- Charcot-Marie-Tooth Disease
- Mutation
- Neurodegenerative Diseases
- rab GTP-Binding Proteins