Synthesis of silk fibroin micro- and submicron spheres using a co-flow capillary device.

Mitropoulos, Alexander N; Perotto, Giovanni; Kim, Sunghwan; Marelli, Benedetto; Kaplan, David L; Omenetto, Fiorenzo G · Adv Mater · 2014

basic_science · Level V

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Abstract

A custom-made co-flow capillary device is used to synthesize monodisperse silk fibroin micro- and submicron-spheres with diameters tunable over a wide range of sizes. A model drug release is examined and control of degradation kinetics is obtained by changing sphere diameter.