Immunological principles regulating immunomodulation with biomaterials.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24342045.
- Also identified by DOI 10.1016/j.actbio.2013.12.011.
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Abstract
The immune system has evolved to recognize and eliminate pathogens; this recognition relies on the identification of structural molecular patterns within unique tissue microenvironments. Therefore, bioengineers can harness these immunological cues to design materials that modulate innate and adaptive immunity in a controlled manner. This review acts as an immunology primer by focusing on the basic molecular and cellular immunology principles governing immunomodulation with biomaterials.
Medical subject headings
- Biocompatible Materials
- Immunity
- Immunomodulation