Photo-crosslinkable PEG-based microribbons for forming 3D macroporous scaffolds with decoupled niche properties.

Han, Li-Hsin; Tong, Xinming; Yang, Fan · Adv Mater · 2014

basic_science · Level V

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Abstract

PEG-based microribbons are designed and fabricated as building blocks for constructing a 3D cell niche with independently tunable biochemical, mechanical, and topographical cues. This platform supports direct cell encapsulation, allows spatial patterning of biochemical cues, and may provide a valuable tool for facilitating the analyses of how interactive niche signaling regulates cell fate in three dimensions.

Medical subject headings