High-density polymer microarrays: identifying synthetic polymers that control human embryonic stem cell growth.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24353271.
- Also identified by DOI 10.1002/adhm.201300489.
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Abstract
The fabrication of high-density polymer microarray is described, allowing the simultaneous and efficient evaluation of more than 7000 different polymers in a single-cellular-based screen. These high-density polymer arrays are applied in the search for synthetic substrates for hESCs culture. Up-scaling of the identified hit polymers enables long-term cellular cultivation and promoted successful stem-cell maintenance.
Medical subject headings
- Embryonic Stem Cells
- Polymers