Improving the clinical evidence of bone graft substitute technology in lumbar spine surgery.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24353975.
- Also identified by DOI 10.1055/s-0032-1315454 and PMC identifier 3864464.
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Abstract
Bone graft substitutes have been used routinely for spine fusion for decades, yet clinical evidence establishing comparative data remains sparse. With recent scrutiny paid to the outcomes, complications, and costs associated with osteobiologics, a need to improve available data guiding efficacious use exists. We review the currently available clinical literature, studying the outcomes of various biologics in posterolateral lumbar spine fusion, and establish the need for a multicenter, independent osteobiologics registry.
Anatomy
- lumbar spine