Live human nasal epithelial cells (hNECs) on chip for in vitro testing of gaseous formaldehyde toxicity via airway delivery.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24356185.
- Also identified by DOI 10.1039/c3lc51208h.
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Abstract
Cell models based on human nasal epithelial stem/progenitor cells (hNESPCs) are developed to obtain functional ciliated cells on modified Transwell inserts. The live hNECs are integrated into microfluidic platforms to mimic the 3D features of the human upper airway for in vitro testing of gaseous formaldehyde toxicity via airway delivery.
Medical subject headings
- Formaldehyde
- Microfluidic Analytical Techniques
- Nasal Mucosa
- Respiratory System
- Toxicity Tests