Toward effective probiotics for autism and other neurodevelopmental disorders.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24360269.
- Also identified by DOI 10.1016/j.cell.2013.11.035 and PMC identifier 4166551.
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Abstract
Hsaio and colleagues link gut microbes to autism spectrum disorders (ASD) in a mouse model. They show that ASD symptoms are triggered by compositional and structural shifts of microbes and associated metabolites, but symptoms are relieved by a Bacteroides fragilis probiotic. Thus probiotics may provide therapeutic strategies for neurodevelopmental disorders.
Medical subject headings
- Child Development Disorders, Pervasive
- Gastrointestinal Tract