Are short telomeres hallmarks of cancer recurrence?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24366690.
- Also identified by DOI 10.1158/1078-0432.CCR-13-3198 and PMC identifier 3944321.
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Abstract
Exposure to radiation and some chemotherapeutic agents is associated with an increased risk of developing second cancers. Short telomeres are almost universally associated with malignant cancer progression. An unanswered question is whether inherited short telomeres or therapy-related telomere shortening is a biomarker of the development of second malignant neoplasms.
Medical subject headings
- Hodgkin Disease
- Neoplasms, Second Primary
- Telomere
- Thyroid Neoplasms