Children with severe asthma have unique oxidative stress-associated metabolomic profiles.
Level V
Where this comes from
- Record sourced from PubMed, PMID 24369802.
- Also identified by DOI 10.1016/j.jaci.2013.10.012 and PMC identifier 3915866.
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Abstract
Children with severe asthma have unique metabolic derangements associated with oxidative stress-related pathways. These metabolic differences may contribute to corticosteroid insensitivity in severe asthma and may be novel targets for further study and therapeutic intervention.
Medical subject headings
- Asthma
- Ethanolamines
- Glycine
- Oxidative Stress
- Serine
- Sphingosine N-Acyltransferase
- Threonine