HTS navigator: freely accessible cheminformatics software for analyzing high-throughput screening data.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24376084.
- Also identified by DOI 10.1093/bioinformatics/btt718 and PMC identifier 3928525.
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Abstract
We report on the development of the high-throughput screening (HTS) Navigator software to analyze and visualize the results of HTS of chemical libraries. The HTS Navigator processes output files from different plate readers' formats, computes the overall HTS matrix, automatically detects hits and has different types of baseline navigation and correction features. The software incorporates advanced cheminformatics capabilities such as chemical structure storage and visualization, fast similarity search and chemical neighborhood analysis for retrieved hits. The software is freely available for academic laboratories. http://fourches.web.unc.edu/
Medical subject headings
- Computational Biology
- High-Throughput Screening Assays
- Information Storage and Retrieval
- Small Molecule Libraries
- Software