Facile fabrication of polyanhydride/anesthetic nanoparticles with tunable release kinetics.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24376136.
- Also identified by DOI 10.1002/adhm.201300521 and PMC identifier 4053479.
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Abstract
This work illustrates a two-step strategy for the fabrication of polymer/drug nanoparticles. Utilizing solvent/non-solvent precipitation and gaseous basification, composite nanoparticles with 0-100% drug loadings are fabricated. Drug release kinetics are dictated by nanoparticle composition allowing future tuning for therapeutic applications.
Medical subject headings
- Anesthetics
- Nanoparticles
- Polyanhydrides