A new approach to iliac bone histomorphometry: implications for biomechanics and cell biology.

Parfitt, A Michael · J Clin Invest · 2014

basic_science · Level V

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Abstract

I devised a method for obtaining information on cancellous bone structure from iliac bone histomorphometry that led to the demonstration that architecture is an important component of bone strength and bone fragility. Furthermore, this method contributed to the recognition of the importance of changes in osteoclast and osteocyte apoptosis in response to estrogen deficiency and replacement.

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