IgG4-related leptomeningitis: a reversible cause of rapidly progressive cognitive decline.

Mehta, Shyamal H; Switzer, Jeffrey A; Biddinger, Paul; Rojiani, Amyn M · Neurology · 2014

case_report · Level V

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Abstract

Immunoglobulin G4-related diseases (IgG4-RD) are a newly recognized category of diseases. CNS involvement in IgG4-RD includes hypophysitis(1) and intracranial or spinal manifestations of hypertrophic pachymeningitis.(2,3) We present a unique case of rapid cognitive decline due to IgG4-related leptomeningitis.

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