The race for regeneration: Pluripotent-stem-cell-derived 3D kidney structures.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24388170.
- Also identified by DOI 10.1016/j.stem.2013.12.004 and PMC identifier 4058857.
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Abstract
The kidney's complex spatial organization and poorly defined lineage specification programs have impeded derivation of kidney progenitors from pluripotent stem cells (PSCs). Now in Cell Stem Cell, Taguchi et al. (2014) redefine the identity of embryonic kidney progenitors in vivo to obtain PSC-derived kidney progenitors that can form nephrons in vivo.
Medical subject headings
- Cell Differentiation
- Embryonic Stem Cells
- Induced Pluripotent Stem Cells
- Kidney
- Mesoderm
- Nephrons
- Organogenesis