MALAdaptive: do we avoid metformin unnecessarily?
Level V
Where this comes from
- Record sourced from PubMed, PMID 24390895.
- Also identified by DOI 10.3122/jabfm.2014.01.120173.
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Abstract
Convention holds that the use of metformin is contraindicated in many patients secondary to concerns about lactic acidosis. However, current evidence suggests that metformin-associated lactic acidosis is at most idiosyncratic. Awareness of the current evidence should permit broader use of this valuable medication.