Liquid and back gate coupling effect: toward biosensing with lowest detection limit.

Pud, Sergii; Li, Jing; Sibiliev, Volodymyr; Petrychuk, Mykhaylo; Kovalenko, Valery; Offenhäusser, Andreas; Vitusevich, Svetlana · Nano Lett · 2014

basic_science · Level V

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Abstract

We employ noise spectroscopy and transconductance measurements to establish the optimal regimes of operation for our fabricated silicon nanowire field-effect transistors (Si NW FETs) sensors. A strong coupling between the liquid gate and back gate (the substrate) has been revealed and used for optimization of signal-to-noise ratio in subthreshold as well as above-threshold regimes. Increasing the sensitivity of Si NW FET sensors above the detection limit has been predicted and proven by direct experimental measurements.

Medical subject headings