Engineered micro-objects as scaffolding elements in cellular building blocks for bottom-up tissue engineering approaches.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24395427.
- Also identified by DOI 10.1002/adma.201304539.
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Abstract
A material-based bottom-up approach is proposed towards an assembly of cells and engineered micro-objects at the macroscale. We show how shape, size and wettability of engineered micro-objects play an important role in the behavior of cells on these objects. This approach can, among other applications, be used as a tool to engineer complex 3D tissues of clinically relevant size.
Medical subject headings
- Microtechnology
- Tissue Engineering
- Tissue Scaffolds