Regenerative medicine: Cartilage transplants hold promise for challenging bone defects.

Nishitani, Kohei; Schwarz, Edward M · Nat Rev Rheumatol · 2014

basic_science · Level V

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Abstract

The challenges of healing have led investigators to question existing paradigms in the hopes of uncovering overlooked solutions. Such is the case in a recent study showing that introduction of a cartilage construct into a mouse tibial defect induces remarkable healing owing to the transformation of donor chondrocytes into new bone.

Medical subject headings