Epigenetics in 2013. DNA methylation and miRNA: key roles in systemic autoimmunity.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24418763.
- Also identified by DOI 10.1038/nrrheum.2013.211 and PMC identifier 4332710.
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Abstract
Several advances in 2013 have improved our understanding of how epigenetic mechanisms affect autoimmune disorders. Many new insights were made into the regulation of gene expression by DNA methylation in systemic lupus erythematosus. For rheumatoid arthritis, complex interrelationships between DNA methylation and microRNAs in regulating gene expression were described.
Medical subject headings
- Autoimmunity
- DNA Methylation
- MicroRNAs