High aspect ratio elongated microparticles for enhanced topical drug delivery in human volunteers.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 24421280.
- Also identified by DOI 10.1002/adhm.201300517.
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Abstract
Delivery of therapeutics into skin is hindered by the epidermal barriers. To overcome these barriers for the treatment of skin diseases, a cutaneous delivery method capable of field treatment using silica-elongated microparticles is developed. The microparticles are massaged into the skin using a 3D-printed microtextured applicator resulting in significant field-directed drug delivery enhancement.
Medical subject headings
- Drug Carriers
- Microspheres
- Skin