Proteoglycans and glycosaminoglycans improve toughness of biocompatible double network hydrogels.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24431128.
- Also identified by DOI 10.1002/adma.201303387.
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Abstract
Based on the molecular stent concept, a series of tough double-network hydrogels (St-DN gels) made from the components of proteoglycan aggregates - chondroitin sulfate proteoglycans (1), chondroitin sulfate (2), and sodium hyaluronate (3) - are successfully developed in combination with a neutral biocompatible polymer. This work demonstrates a promising method to create biopolymer-based tough hydrogels for biomedical applications.
Medical subject headings
- Biocompatible Materials
- Chondroitin Sulfate Proteoglycans
- Chondroitin Sulfates
- Hyaluronic Acid
- Hydrogels
- Polymers