Medicine. How thalidomide works against cancer.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24436409.
- Also identified by DOI 10.1126/science.1249543 and PMC identifier 4084783.
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Abstract
The surprising ability of thalidomude and its analogs to treat various hematologic malignancies is through the loss of two transcription factors.
Medical subject headings
- Antineoplastic Agents
- Ikaros Transcription Factor
- Multiple Myeloma
- Peptide Hydrolases
- Teratogens
- Thalidomide