The shape of things to come.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24439365.
- Also identified by DOI 10.1016/j.cell.2013.12.037.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Surface receptors can link binding of ligands to changes in the actin-based cell cytoskeleton. Chia et al. and Chen et al. provide evidence for direct binding between the cytoplasmic tails of receptors and the WAVE complex, a regulator of the actin nucleator Arp2/3 complex, which might help to explain how environmental signals are translated into changes in morphology and motility.
Medical subject headings
- Actin Cytoskeleton
- Actins
- Axons
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Drosophila melanogaster
- Immunoglobulins
- Membrane Proteins
- Multiprotein Complexes
- Synapses
- Wiskott-Aldrich Syndrome Protein Family